HS-AFM Movies

High-Speed AFM Height Spectroscopy (HS-AFM-HS): Microsecond dynamics of unlabeled biomolecules
Nature Communications, 2018, 9(1):4983. doi:10.1038/s41467-018-07512-3
George Heath & Simon Scheuring*


An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel
Nature Communications, 2018, 9(1):3978. doi:10.1038/s41467-018-06414-8.
Arin Marchesi, Xiaolong Gao, Ricardo Adaixo, Jan Rheinberger, Henning Stahlberg, Crina Nimigean* & Simon Scheuring*


Structural titration of receptor ion channel GLIC gating by HS-AFM
PNAS, 2018, doi.org/10.1073/pnas.1805621115
Yi Ruan, Kevin Kao, Solène Lefebvre, Arin Marchesi, Pierre-Jean Corringer Richard K Hite & Simon Scheuring*


High-speed AFM reveals the inner workings of the MinDE protein oscillator
Nano Letters, 2018, 18(1):288–296, doi:10.1021/acs.nanolett.7b04128
Atsushi Miyagi#, Beatrice Ramm#, Petra Schwille & Simon Scheuring*


Lysenin toxin membrane insertion is pH-dependent and non-cooperative
Biophys J, 2017, 113(9):2029-2036, doi.org/10.1016/j.bpj.2017.08.056
Ignacio Munguira#, Hirohide Takahashi#, Ignacio Casuso & Simon Scheuring*


Dynamic subunit turnover in ESCRT-III assemblies is regulated by Vps4 to mediate membrane remodelling during cytokinesis
Nature Cell Biology, 2017, 19(7): Jun 12. doi: 10.1038/ncb3559
Beata Mierzwa#, Nicolas Chiaruttini#, Lorena Redondo-Morata#, Joachim Moser von Filseck, Julia König, Jorge Larios, Ina Poser, Thomas Müller-Reichert, Simon Scheuring, Aurélien Roux* & Daniel Gehrlich*


Dynamin-dependent membrane constriction and fission observed by High-Speed AFM
PNAS, 2017, 114(21):5449-5454. doi: 10.1073/pnas.1619578114
Adai Colom, Lorena Redondo-Morata, Nicolas Chiaruttini, Aurélien Roux* & Simon Scheuring*


Real-time Visualization of Phospholipid Degradation by Outer Membrane Phospholipase A using High-Speed Atomic Force Microscopy
J Mol Biol, 2017, 429(7):977–986; doi.org/10.1016/j.jmb.2017.03.004
Martina Rangl, Luca Rima, Jessica Klement, Atsushi Miyagi, Sandro Keller* & Simon Scheuring*


Direct visualization of glutamate transporter elevator mechanism in substrate transport by high-speed AFM
PNAS, 2017, 114(7):1584-1588; doi: 10.1073/pnas.1616413114
Yi Ruan, Atsushi Miyagi, Xiaoyu Wang, Mohamed Chami, Olga Boudker* & Simon Scheuring*


Temperature-controlled high-speed AFM: Real time observation of ripple-phase transitions.
Small, 2016, 12(44):6106-6113
Hirohide Takahashi#, Atsushi Miyagi# Lorena Redondo-Morata & Simon Scheuring*


Automated force controller for amplitude modulation AFM.
Review of Scientific Instruments, 2016, 87(5): doi.org/10.1063/1.4950777
Atsushi Miyagi* & Simon Scheuring*


Real-time visualization of conformational changes upon ligand unbinding from single MloK1 cyclic nucleotide-modulated channels.
Nature Communications, 2016, 7: doi:10.1038/ncomms12789
Martina Rangl, Atsushi Miyagi, Julia Kowal, Henning Stahlberg, Crina Nimigean* & Simon Scheuring*


High-speed atomic force microscopy shows that annexin-V stabilizes membranes on the second timescale.
Nature Nanotechnology, 2016, 11: 783-790
Atsushi Miyagi, Martina Rangl, Christophe Chipot & Simon Scheuring*


Listeriolysin-O membrane damaging activity involves arc formation and lineaction – implication for Listeria monocytogenes escape from phagocytic vacuole.
PLOS Pathogens, 2016, 12(4):e1005597. doi: 10.1371/journal.ppat.1005597
Yi Ruan, Sasa Rezelj, Apolonija Bedina Zavec, Gregor Anderluh* & Simon Scheuring* 


Glass-like membrane protein diffusion in a crowded membrane.
ACS Nano, 2016, 10(2): 2584-2590
Ignacio LB Munguira#, Ignacio Casuso#, Hirohide Takahashi, Felix Rico, Atsushi Miyagi, Mohamed Chami & Simon Scheuring*


Compression of ESCRT-III spiral springs drives membrane deformation.
Cell, 2015, in press
Nicolas Chiaruttini#, Lorena Redondo#, Frédéric Humbert, Martin Lenz*, Simon Scheuring*, Aurélien Roux*


A hybrid high-speed atomic force-optical microscope for visualising single membrane proteins on eukaryotic cells
Nature Communications, 2013, 4: 2155, DOI:10.1038/ncomms3155
Adai Colom#, Ignacio Casuso#, Felix Rico & Simon Scheuring*


High-speed atomic force microscopy: Cooperative adhesion and dynamic equilibrium of junctional microdomain membrane proteins
J Mol Biol, 2012, 423 (2): 249-256
Adai Colom, Ignacio Casuso, Thomas Boudier & Simon Scheuring*


Characterization of the motion of membrane proteins using high speed atomic force microscopy
Nature Nanotechnology, 2012, 7 (8): 525-529
Ignacio Casuso, Jonathan Khao, Mohamed Chami, Perrine Paul-Gilloteaux, Mohamed Husain, Jean-Pierre Duneau, Henning Stahlberg, James N Sturgis & Simon Scheuring* 

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Experimental evidence for membrane-mediated protein-protein interaction
Biophys J, 2010, 99 (7): L47-49, doi: 10.1016/j.bpj.2010.07.028
Ignacio Casuso, Pierre Sens, Felix Rico & Simon Scheuring*

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Contact-mode high-resolution high-speed atomic force microscopy movies of the purple membrane
Biophys J, 2009, 97 (5): 1354-1361
Ignacio Casuso, Noriyuki Kodera, Christian Le Grimellec, Toshio Ando & Simon Scheuring*